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At 3 times write-up-MPTP, we observed considerable microglial activation and up-regulation of CB2 cannabinoid receptors in the ventral midbrain. Remedy with Earn or the CB2 receptor agonist JWH015 (4 mg/kg, intraperitoneal) lowered MPTP-induced microglial activation, Whilst genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. In addition, Continual Gain reversed https://win55.clinic/casino

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