Contraindicated (one)pentobarbital will decrease the extent or influence of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is liable for the development and elimination of cariprazine's active metabolites. pentobarbital will lower the extent or impact of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabol... https://nembutalpentobarbital66307.topbloghub.com/41087136/not-known-factual-statements-about-pentobarbital-sodium-price