Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors from the central nervous system, conolidine modulates alternate molecular targets. A Science Advances review discovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By https://spencerktttc.bloginder.com/38607363/not-known-factual-statements-about-alternative-natural-pain-relief-to-replace-traditional-painkillers